黑种草子化学成分和药理研究进展

李雅丽，王增尚，刘博，陈望阳，刘江云，木胡牙提·乌拉斯汉

中国药学杂志 ›› 2016, Vol. 51 ›› Issue (14) : 1157-1161.

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中国药学杂志
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中国药学杂志 ›› 2016, Vol. 51 ›› Issue (14) : 1157-1161. DOI: 10.11669/cpj.2016.14.001
“一带一路”沿线国家传统药物研究专栏

黑种草子化学成分和药理研究进展

  • 李雅丽1，王增尚2，刘博2，陈望阳2，刘江云2*，木胡牙提·乌拉斯汉1
作者信息 +

Advance in Research on Chemical Constituents and Pharmacological Effects of Nigella Seeds

  • LI Ya-li1, WANG Zeng-shang2, LIU Bo2, CHEN Wang-yang2, LIU Jiang-yun2*, MUHUYATI Wulasian2
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文章历史 +

摘要

黑种草属(Nigella)植物主要分布于全球西南亚、南欧、北非等地区，其种子在伊斯兰国家广泛作为传统食品和民族药使用。近30年来的现代研究发现，黑种草子中含有油脂、挥发油、皂苷、黄酮、生物碱等多种化学成分，具有抗氧化、抗炎、抗肿瘤、降血脂等多方面药理作用。笔者对近5年来黑种草子的化学成分及药理作用研究进展进行综述，为其进一步深入研究与开发利用提供参考。

Abstract

The plants of Nigella genus distribute worldwide among Southwest Asia, South Europe and North Africa rigions. Their seeds are applied extensively as both traditional food additives and medicinal herbs in all Islamic countries since ancient time. In the past three decades, Nigella seeds were reported to contain fatty acids, volatile oil, saponins, flavonoids, alkaloids, and other constituents. It had pharmacological effects such as antioxidant, anti-infective, anti-tumor, anti-platelet aggregation effects, etc. In this paper, the chemical composition and pharmacological effects of Nigella seeds in the recent five years are reviewed, which may be helpful for further investigations of these valuable herbs.

关键词

黑种草子 / 化学成分 / 药理作用 / 炎症 / 肿瘤

Key words

Nigella seed / chemical constituent / pharmacological effect / inflammation / cancer

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李雅丽，王增尚，刘博，陈望阳，刘江云，木胡牙提·乌拉斯汉. 黑种草子化学成分和药理研究进展[J]. 中国药学杂志, 2016, 51(14): 1157-1161 https://doi.org/10.11669/cpj.2016.14.001
LI Ya-li, WANG Zeng-shang, LIU Bo, CHEN Wang-yang, LIU Jiang-yun, MUHUYATI Wulasian. Advance in Research on Chemical Constituents and Pharmacological Effects of Nigella Seeds[J]. Chinese Pharmaceutical Journal, 2016, 51(14): 1157-1161 https://doi.org/10.11669/cpj.2016.14.001
中图分类号： R284   

参考文献

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基金

国家自然科学基金资助项目(81274190,81460634)
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